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The rapidly increasing volume of information contained in relational databases places a strain on databases, performance, and maintainability: DBAs are under greater pressure than ever to optimize database structure for system performance and administration. Physical Database Design discusses the concept of how physical structures of databases affect performance, including specific examples, guidelines, and best and worst practices for a variety of DBMSs and configurations. Something as simple as improving the table index design has a profound impact on performance. Every form

Database design --- Bases de données --- Conception --- Database design. --- Data base design --- System design --- Bases de données --- Information Technology --- General and Others --- Informatica --- Systeemontwikkeling

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Create strange lands filled with mysterious objects (cows frozen in blocks of ice, chirping penguins, golden globes with wavering eyes) and throw away your keyboard and mouse, to go exploring armed only with a gamepad, power glove, or just your bare hands! Java gaming expert Andrew Davison will show you how to develop and program 3D games in Java technology on a PC, with an emphasis on the construction of 3D landscapes. It's assumed you have a reasonable knowledge of Java—the sort of thing picked up in a first Java course at school. Topics are split into three sections: Java 3D API, non-standard input devices for game playing, and JOGL. Java 3D is a high-level 3D graphics API, and JOGL is a lower-level Java wrapper around the popular OpenGL graphics API. You'll look at three non-standard input devices: the webcam, the game pad, and the P5 data glove. Along the way, you'll utilize several other games-related libraries including: JInput, JOAL, JMF, and Odejava. Learn all the latest Java SE 6 features relevant to gaming, including: splash screens, JavaScript scripting as well as the desktop and system tray interfaces. Unique coverage of Java game development using both the Java 3D API and Java for OpenGL, as well as invaluable experience from a recognized Java gaming guru, will provide you with a distinct advantage after reading this book.

Java (Computer program language) --- Computer games --- Design --- Information Technology --- Computer Science (Hardware & Networks) --- Design. --- Object-oriented programming languages --- JavaSpaces technology --- Computer games - Design --- Video games

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Information Modeling and Relational Databases, second edition, provides an introduction to ORM (Object-Role Modeling)and much more. In fact, it is the only book to go beyond introductory coverage and provide all of the in-depth instruction you need to transform knowledge from domain experts into a sound database design. This book is intended for anyone with a stake in the accuracy and efficacy of databases: systems analysts, information modelers, database designers and administrators, and programmers. Terry Halpin, a pioneer in the development of ORM, blends conceptual information with

Database design --- Relational databases --- Bases de données --- Bases de données relationnelles --- Conception --- Database design. --- Relational databases. --- Bases de données --- Bases de données relationnelles --- Information Technology --- General and Others --- Relational data bases --- Databases --- Data base design --- System design

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Even at the beginning of the 21st century, we are far from becoming paperless. Pen and paper is still the only truly ubiquitous information processing technology. Pen-and-paper user interfaces bridge the gap between paper and the digital world. Rather than replacing paper with electronic media, they seamlessly integrate both worlds in a hybrid user interface. Classical paper documents become interactive. This opens up a huge field of novel computer applications at our workplaces and in our homes. This book provides readers with a broad and extensive overview of the field, so as to provide a full and up-to-date picture of pen-and-paper computing. It covers the underlying technologies, reviews the variety of modern interface concepts and discusses future directions of pen-and-paper computing. Based on the author’s award-winning dissertation, the book also provides the first theoretical interaction model of pen-and-paper user interfaces and an integrated set of interaction techniques for knowledge workers. The model proposes a ‘construction set’ of core interactions that are helpful in designing solutions that address the diversity of pen-and-paper environments. The interaction techniques, concrete instantiations of the model, provide innovative support for working with printed and digital documents. They integrate well-established paper-based practices with concepts derived from hypertext and social media. Researchers, practitioners who are considering deploying pen-and-paper user interfaces in real-world projects, and interested readers from other research disciplines will find the book an invaluable reference source. Also, it provides an introduction to pen-and-paper computing for the academic curriculum. The present book was overdue: a thorough, concise, and well-organized compendium of marriages between paper-based and electronic documents. Max Mühlhäuser, Technische Universität Darmstadt Everyone interested in how to design for real-world activities would profit from reading this book. James D. Hollan, University of California, San Diego.

Computer systems. --- Human-computer interaction. --- User interfaces (Computer systems). --- Engineering & Applied Sciences --- Applied Mathematics --- Computer Science --- User-centered system design. --- User interfaces (Computer systems) --- Interfaces, User (Computer systems) --- Computer-human interaction --- Human factors in computing systems --- Interaction, Human-computer --- Cognitive engineering (System design) --- Participatory design (System design) --- UCD (System design) --- Usability engineering (System design) --- User-centered design (System design) --- Mathematics. --- Applied mathematics. --- Engineering mathematics. --- Applications of Mathematics. --- User Interfaces and Human Computer Interaction. --- Engineering --- Engineering analysis --- Mathematical analysis --- Human-machine systems --- Human-computer interaction --- Math --- Science --- Mathematics --- Human engineering --- User-centered system design --- System design --- Computer science. --- Informatics

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Quand Horace Walpole a inventé la science qu'il appela de ce doux néologisme qu'est sérendipité, il mit enfin un nom à un concept clé dans la recherche : le hasard. Les chemins qui mènent à la découverte de médicaments ne sont pas tous gravés dans le marbre de la science ou de l'orthodoxie des procédures, loin s'en faut : un fabuleux hasard est souvent intervenu, servi par l'intuition ou l'attention de chercheurs ; l'étude et l'exploitation de ce hasard a donné naissance à cette « sérendipité », science initiée par les anglo-saxons. Cet ouvrage retrace les chemins parcourus pour mener à la découverte d'une trentaine de médicaments qui ont tous en commun ce parcours original. Il en est ainsi d'histoires illustres comme celles de la découverte de la pénicilline par Fleming ou de l'insuline par Banting et Best mais aussi d'autres moins connues, révélées par l'enquête des auteurs, comme le modafinil (lutte contre le sommeil) ou la cyclosporine (greffe d'organes). ›La sérendipité a contribué également au renouveau de larges secteurs thérapeutiques, comme la psychiatrie dans les années 50, lorsque des médicaments comme le Largactil®, le Valium® ou les benzodiazépines ont fait leur apparition, ou la cancérologie, avec le cis-platine, la navelbine ou le taxotère. Hasard toujours présent dans ce qui a constitué l'un des éléments de la libération de la femme, la découverte de la pilule. Au-delà de la simple histoire de la découverte de nouveaux médicaments, cet ouvrage met également en exergue la persévérance de certains chercheurs comme Henri Laborit dont le nom est lié à celui du Largactil®, Frank Berger à celui de l'Equanil®, Roland Kuhn à celui de l'imipramine (Tofranil®) et Ernest Fourneau et Auguste-Louis Loubatières à celui des sulfamides antibactériens et hypoglycémiants. Ces nombreux exemples valorisent le travail des chercheurs qui, parfois au péril de leur vie comme pour Roger Althounyan (antihistaminique) ou John Cade (lithium), ont su faire triompher leurs recherches ; car comme l'affirmait Pasteur, le hasard ne favorise que des esprits préparés…

Drug development. --- Drugs --- Pharmaceutical chemistry --- Design. --- History. --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Drug design --- Pharmaceutical design --- Development of drugs --- New drug development --- Chemistry --- Development --- Drug development --- Pharmacology --- Pharmacy